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Prajwal Gurung
Prajwal Gurung
Associate Professor at the University of Iowa
Verified email at uiowa.edu
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Cited by
Year
RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3
CP Dillon, R Weinlich, DA Rodriguez, JG Cripps, G Quarato, P Gurung, ...
Cell 157 (5), 1189-1202, 2014
5592014
FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes
P Gurung, PK Anand, RK Malireddi, L Vande Walle, N Van Opdenbosch, ...
The Journal of Immunology 192 (4), 1835-1846, 2014
5322014
Mitochondria: diversity in the regulation of the NLRP3 inflammasome
P Gurung, JR Lukens, TD Kanneganti
Trends in molecular medicine 21 (3), 193-201, 2015
3752015
Critical role for the DNA sensor AIM2 in stem cell proliferation and cancer
SM Man, Q Zhu, L Zhu, Z Liu, R Karki, A Malik, D Sharma, L Li, ...
Cell 162 (1), 45-58, 2015
3092015
Dietary modulation of the microbiome affects autoinflammatory disease
JR Lukens, P Gurung, P Vogel, GR Johnson, RA Carter, DJ McGoldrick, ...
Nature 516 (7530), 246-249, 2014
2972014
Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4 …
P Gurung, RKS Malireddi, PK Anand, D Demon, LV Walle, Z Liu, P Vogel, ...
Journal of Biological Chemistry 287 (41), 34474-34483, 2012
2702012
Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection
R Karki, SM Man, RKS Malireddi, P Gurung, P Vogel, M Lamkanfi, ...
Cell host & microbe 17 (3), 357-368, 2015
2622015
Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation
N Van Opdenbosch, P Gurung, L Vande Walle, A Fossoul, TD Kanneganti, ...
Nature communications 5 (1), 3209, 2014
2492014
Recent advances in lipopolysaccharide recognition systems
L Mazgaeen, P Gurung
International journal of molecular sciences 21 (2), 379, 2020
2402020
Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity–independent pyroptosis, apoptosis, necroptosis, and inflammatory disease
RK Malireddi, P Gurung, S Kesavardhana, P Samir, A Burton, ...
Journal of Experimental Medicine 217 (3), 2020
2082020
TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation
RKS Malireddi, P Gurung, J Mavuluri, TK Dasari, JM Klco, H Chi, ...
Journal of Experimental Medicine 215 (4), 1023-1034, 2018
1862018
Novel roles for caspase-8 in IL-1β and inflammasome regulation
P Gurung, TD Kanneganti
The American journal of pathology 185 (1), 17-25, 2015
1832015
Protective roles for caspase-8 and cFLIP in adult homeostasis
R Weinlich, A Oberst, CP Dillon, LJ Janke, S Milasta, JR Lukens, ...
Cell reports 5 (2), 340-348, 2013
1652013
Role of inflammasomes in host defense against Citrobacter rodentium infection
Z Liu, MH Zaki, P Vogel, P Gurung, BB Finlay, W Deng, M Lamkanfi, ...
Journal of Biological chemistry 287 (20), 16955-16964, 2012
1572012
NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells
SW Paugh, EJ Bonten, D Savic, LB Ramsey, WE Thierfelder, P Gurung, ...
Nature genetics 47 (6), 607-614, 2015
1562015
Chronic TLR stimulation controls NLRP3 inflammasome activation through IL-10 mediated regulation of NLRP3 expression and caspase-8 activation
P Gurung, B Li, RK Subbarao Malireddi, M Lamkanfi, TL Geiger, ...
Scientific reports 5 (1), 14488, 2015
1532015
Cutting edge: STING mediates protection against colorectal tumorigenesis by governing the magnitude of intestinal inflammation
Q Zhu, SM Man, P Gurung, Z Liu, P Vogel, M Lamkanfi, TD Kanneganti
The Journal of Immunology 193 (10), 4779-4782, 2014
1432014
An NLRP3 inflammasome–triggered Th2-biased adaptive immune response promotes leishmaniasis
P Gurung, R Karki, P Vogel, M Watanabe, M Bix, M Lamkanfi, ...
The Journal of clinical investigation 125 (3), 1329-1338, 2015
1312015
The NLRP12 sensor negatively regulates autoinflammatory disease by modulating interleukin-4 production in T cells
JR Lukens, P Gurung, PJ Shaw, MJ Barr, MH Zaki, SA Brown, P Vogel, ...
Immunity 42 (4), 654-664, 2015
1152015
NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1β–mediated osteomyelitis
P Gurung, A Burton, TD Kanneganti
Proceedings of the National Academy of Sciences 113 (16), 4452-4457, 2016
1092016
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