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Alexandro E Trevino
Alexandro E Trevino
Enable Medicine
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Cited by
Cited by
Year
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
FA Ran, PD Hsu, CY Lin, JS Gootenberg, S Konermann, AE Trevino, ...
Cell 154 (6), 1380-1389, 2013
41492013
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
S Konermann, MD Brigham, AE Trevino, J Joung, OO Abudayyeh, ...
Nature 517 (7536), 583-588, 2015
28572015
An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
MR Corces, AE Trevino, EG Hamilton, PG Greenside, ...
Nature methods 14 (10), 959-962, 2017
17712017
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
X Wu, DA Scott, AJ Kriz, AC Chiu, PD Hsu, DB Dadon, AW Cheng, ...
Nature biotechnology 32 (7), 670-676, 2014
11352014
Optical control of mammalian endogenous transcription and epigenetic states
S Konermann, MD Brigham, AE Trevino, PD Hsu, M Heidenreich, L Cong, ...
Nature 500 (7463), 472-476, 2013
10502013
Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution
AE Trevino, F Müller, J Andersen, L Sundaram, A Kathiria, A Shcherbina, ...
Cell 184 (19), 5053-5069. e23, 2021
2222021
Chromatin accessibility dynamics in a model of human forebrain development
AE Trevino, N Sinnott-Armstrong, J Andersen, SJ Yoon, N Huber, ...
Science 367 (6476), eaay1645, 2020
1952020
Genome editing using Cas9 nickases
AE Trevino, F Zhang
Methods in enzymology 546, 161-174, 2014
1412014
Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements
J Tycko, M Wainberg, GK Marinov, O Ursu, GT Hess, BK Ego, Aradhana, ...
Nature communications 10 (1), 4063, 2019
1012019
Nociceptor neurons affect cancer immunosurveillance
M Balood, M Ahmadi, T Eichwald, A Ahmadi, A Majdoubi, K Roversi, ...
Nature 611 (7935), 405-412, 2022
712022
Diverse lncRNA mechanisms in brain development and disease
CE Ang, AE Trevino, HY Chang
Current opinion in genetics & development 65, 42-46, 2020
472020
Transcription-dependent domain-scale three-dimensional genome organization in the dinoflagellate Breviolum minutum
GK Marinov, AE Trevino, T Xiang, A Kundaje, AR Grossman, ...
Nature Genetics 53 (5), 613-617, 2021
432021
Graph deep learning for the characterization of tumour microenvironments from spatial protein profiles in tissue specimens
Z Wu, AE Trevino, E Wu, K Swanson, HJ Kim, HB D’Angio, R Preska, ...
Nature Biomedical Engineering 6 (12), 1435-1448, 2022
422022
Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems
S Konermann, A Trevino, M Brigham, RAN Fei, P Hsu, C Lin, O Nureki, ...
US Patent 10,550,372, 2020
332020
Functional screening with optimized functional CRISPR-Cas systems
F Zhang, S Konermann, MD Brigham, A Trevino
US Patent 11,001,829, 2021
282021
7-UP: Generating in silico CODEX from a small set of immunofluorescence markers
E Wu, AE Trevino, Z Wu, K Swanson, HJ Kim, HB D’Angio, R Preska, ...
PNAS nexus 2 (6), pgad171, 2023
102023
Single‐Cell Transcriptomic Census of Endothelial Changes Induced by Matrix Stiffness and the Association with Atherosclerosis
M Zamani, YH Cheng, F Charbonier, VK Gupta, AT Mayer, AE Trevino, ...
Advanced functional materials 32 (47), 2203069, 2022
102022
SPACE-GM: geometric deep learning of disease-associated microenvironments from multiplex spatial protein profiles
Z Wu, AE Trevino, E Wu, K Swanson, HJ Kim, HB D’Angio, R Preska, ...
bioRxiv, 2022.05. 12.491707, 2022
72022
emObject: domain specific data abstraction for spatial omics
EAG Baker, MY Huang, A Lam, MK Rahim, MF Bieniosek, B Wang, ...
bioRxiv, 2023.06. 07.543950, 2023
42023
Deriving spatial features from in situ proteomics imaging to enhance cancer survival analysis
MT Dayao, A Trevino, H Kim, M Ruffalo, HB D’Angio, R Preska, U Duvvuri, ...
Bioinformatics 39 (Supplement_1), i140-i148, 2023
32023
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Articles 1–20