| Rational design and synthesis of novel dimeric diketoacid-containing inhibitors of HIV-1 integrase: implication for binding to two metal ions on the active site of integrase YQ Long, XH Jiang, R Dayam, T Sanchez, R Shoemaker, S Sei, ... Journal of medicinal chemistry 47 (10), 2561-2573, 2004 | 238 | 2004 |
| Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore J Deng, T Sanchez, LQ Al-Mawsawi, R Dayam, RA Yunes, A Garofalo, ... Bioorganic & medicinal chemistry 15 (14), 4985-5002, 2007 | 210 | 2007 |
| Design and synthesis of novel indole β-diketo acid derivatives as HIV-1 integrase inhibitors M Sechi, M Derudas, R Dallocchio, A Dessì, A Bacchi, L Sannia, F Carta, ... Journal of medicinal chemistry 47 (21), 5298-5310, 2004 | 175 | 2004 |
| β-Diketo acid pharmacophore hypothesis. 1. Discovery of a novel class of HIV-1 integrase inhibitors R Dayam, T Sanchez, O Clement, R Shoemaker, S Sei, N Neamati Journal of medicinal chemistry 48 (1), 111-120, 2005 | 157 | 2005 |
| Discovery of small molecule integrin αvβ3 antagonists as novel anticancer agents R Dayam, F Aiello, J Deng, Y Wu, A Garofalo, X Chen, N Neamati Journal of medicinal chemistry 49 (15), 4526-4534, 2006 | 156 | 2006 |
| Discovery of novel small-molecule inhibitors of human epidermal growth factor receptor-2: Combined ligand and target-based approach R Gundla, R Kazemi, R Sanam, R Muttineni, JARP Sarma, R Dayam, ... Journal of medicinal chemistry 51 (12), 3367-3377, 2008 | 148 | 2008 |
| Discovery of a small-molecule HIV-1 integrase inhibitor-binding site LQ Al-Mawsawi, V Fikkert, R Dayam, M Witvrouw, TR Burke Jr, ... Proceedings of the National Academy of Sciences 103 (26), 10080-10085, 2006 | 137 | 2006 |
| HIV‐1 integrase inhibitors: 2005–2006 update R Dayam, R Gundla, LQ Al‐Mawsawi, N Neamati Medicinal Research Reviews 28 (1), 118-154, 2008 | 124 | 2008 |
| Quinolone 3-carboxylic acid pharmacophore: design of second generation HIV-1 integrase inhibitors R Dayam, LQ Al-Mawsawi, Z Zawahir, M Witvrouw, Z Debyser, N Neamati Journal of medicinal chemistry 51 (5), 1136-1144, 2008 | 118 | 2008 |
| Small-molecule HIV-1 integrase inhibitors: the 2001-2002 update R Dayam, N Neamati Current pharmaceutical design 9 (22), 1789-1802, 2003 | 112 | 2003 |
| HIV‐1 integrase inhibitors: 2003–2004 update R Dayam, J Deng, N Neamati Medicinal research reviews 26 (3), 271-309, 2006 | 96 | 2006 |
| Diketo acid pharmacophore. 2. Discovery of structurally diverse inhibitors of HIV-1 integrase R Dayam, T Sanchez, N Neamati Journal of medicinal chemistry 48 (25), 8009-8015, 2005 | 85 | 2005 |
| Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors LQ Al-Mawsawi, R Dayam, L Taheri, M Witvrouw, Z Debyser, N Neamati Bioorganic & medicinal chemistry letters 17 (23), 6472-6475, 2007 | 79 | 2007 |
| Design and synthesis of novel dihydroquinoline-3-carboxylic acids as HIV-1 integrase inhibitors M Sechi, G Rizzi, A Bacchi, M Carcelli, D Rogolino, N Pala, TW Sanchez, ... Bioorganic & medicinal chemistry 17 (7), 2925-2935, 2009 | 78 | 2009 |
| Pharmacophore guided discovery of small-molecule human apurinic/apyrimidinic endonuclease 1 inhibitors Z Zawahir, R Dayam, J Deng, C Pereira, N Neamati Journal of medicinal chemistry 52 (1), 20-32, 2009 | 78 | 2009 |
| Active site binding modes of the β-diketoacids: a multi-active site approach in HIV-1 integrase inhibitor design R Dayam, N Neamati Bioorganic & medicinal chemistry 12 (24), 6371-6381, 2004 | 77 | 2004 |
| Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: Insight into integrase–DNA complex formation and catalysis LQ Al-Mawsawi, F Christ, R Dayam, Z Debyser, N Neamati FEBS letters 582 (10), 1425-1430, 2008 | 70 | 2008 |
| HIV-1 integrase inhibitors: an emerging clinical reality R Dayam, LQ Al-Mawsawi, N Neamati Drugs in R & D 8, 155-168, 2007 | 70 | 2007 |
| Discovery and preclinical evaluation of a novel class of small-molecule compounds in hormone-dependent and-independent cancer cell lines C Plasencia, R Dayam, Q Wang, J Pinski, TR Burke Jr, DI Quinn, ... Molecular cancer therapeutics 4 (7), 1105-1113, 2005 | 65 | 2005 |
| Fibroblast growth factor receptor inhibitors S Kumar BVS, L Narasu, R Gundla, R Dayam, S JARP Current pharmaceutical design 19 (4), 687-701, 2013 | 47 | 2013 |
Prof. Rambabu Gundla, Ph.DFormer HoD & Professor, Dept. of Chemistry, School of ScienceGITAM University, HydEmail verificata su gitam.edu
