| Evolution of genes and genomes on the Drosophila phylogeny AG Clark, L Pachter Nature 450 (7167), 203-218, 2007 | 2062 | 2007 |
| Wisdom of crowds for robust gene network inference D Marbach, JC Costello, R Küffner, NM Vega, RJ Prill, DM Camacho, ... Nature methods 9 (8), 796-804, 2012 | 1579 | 2012 |
| A community effort to assess and improve drug sensitivity prediction algorithms JC Costello, LM Heiser, E Georgii, M Gönen, MP Menden, NJ Wang, ... Nature biotechnology 32 (12), 1202-1212, 2014 | 623 | 2014 |
| Next-generation machine learning for biological networks DM Camacho, KM Collins, RK Powers, JC Costello, JJ Collins Cell 173 (7), 1581-1592, 2018 | 562 | 2018 |
| Bactericidal antibiotics induce mitochondrial dysfunction and oxidative damage in mammalian cells S Kalghatgi, CS Spina, JC Costello, M Liesa, JR Morones-Ramirez, ... Science translational medicine 5 (192), 192ra85-192ra85, 2013 | 448 | 2013 |
| Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks D Malhotra, AL Fletcher, J Astarita, V Lukacs-Kornek, P Tayalia, ... Nature immunology 13 (5), 499-510, 2012 | 413 | 2012 |
| Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma LN Kwong, JC Costello, H Liu, S Jiang, TL Helms, AE Langsdorf, ... Nature medicine 18 (10), 1503-1510, 2012 | 348 | 2012 |
| TERT promoter mutations and telomerase reactivation in urothelial cancer S Borah, L Xi, AJ Zaug, NM Powell, GM Dancik, SB Cohen, JC Costello, ... Science 347 (6225), 1006-1010, 2015 | 288 | 2015 |
| A community computational challenge to predict the activity of pairs of compounds M Bansal, J Yang, C Karan, MP Menden, JC Costello, H Tang, G Xiao, ... Nature biotechnology 32 (12), 1213-1222, 2014 | 240 | 2014 |
| Tumor-Derived Cell Lines as Molecular Models of Cancer PharmacogenomicsCancer Cell Lines as Pharmacogenomic Models A Goodspeed, LM Heiser, JW Gray, JC Costello Molecular Cancer Research 14 (1), 3-13, 2016 | 239 | 2016 |
| Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes K Narayan, KE Sylvia, N Malhotra, CC Yin, G Martens, T Vallerskog, ... Nature immunology 13 (5), 511-518, 2012 | 194 | 2012 |
| Crowdsourcing biomedical research: leveraging communities as innovation engines J Saez-Rodriguez, JC Costello, SH Friend, MR Kellen, L Mangravite, ... Nature Reviews Genetics 17 (8), 470-486, 2016 | 149 | 2016 |
| Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid LeukemiaMonocytic AML Is Resistant to Venetoclax S Pei, DA Pollyea, A Gustafson, BM Stevens, M Minhajuddin, R Fu, ... Cancer discovery 10 (4), 536-551, 2020 | 140 | 2020 |
| “Reverse ecology” and the power of population genomics YF Li, JC Costello, AK Holloway, MW Hahn Evolution: International Journal of Organic Evolution 62 (12), 2984-2994, 2008 | 134 | 2008 |
| Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open … J Guinney, T Wang, TD Laajala, KK Winner, JC Bare, EC Neto, SA Khan, ... The Lancet Oncology 18 (1), 132-142, 2017 | 132 | 2017 |
| Transcriptomes of the B and T lineages compared by multiplatform microarray profiling MW Painter, S Davis, RR Hardy, D Mathis, C Benoist, ... The Journal of Immunology 186 (5), 3047-3057, 2011 | 108 | 2011 |
| Concurrent alterations in TERT, KDM6A, and the BRCA pathway in bladder cancer ML Nickerson, GM Dancik, KM Im, MG Edwards, S Turan, J Brown, ... Clinical Cancer Research 20 (18), 4935-4948, 2014 | 104 | 2014 |
| Transcriptome analysis identifies regulators of hematopoietic stem and progenitor cells R Gazit, BS Garrison, TN Rao, T Shay, J Costello, J Ericson, F Kim, ... Stem cell reports 1 (3), 266-280, 2013 | 104 | 2013 |
| GSEA-InContext: identifying novel and common patterns in expression experiments RK Powers, A Goodspeed, H Pielke-Lombardo, AC Tan, JC Costello Bioinformatics 34 (13), i555-i564, 2018 | 80 | 2018 |
| Coordinate loss of MAP3K7 and CHD1 promotes aggressive prostate cancer LU Rodrigues, L Rider, C Nieto, L Romero, A Karimpour-Fard, M Loda, ... Cancer research 75 (6), 1021-1034, 2015 | 78 | 2015 |
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