Tracy Nero
Tracy Nero
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Cited by
Cited by
Oncogenic protein interfaces: small molecules, big challenges
TL Nero, CJ Morton, JK Holien, J Wielens, MW Parker
Nature Reviews Cancer 14 (4), 248-262, 2014
The GM–CSF/IL‐3/IL‐5 cytokine receptor family: from ligand recognition to initiation of signaling
SE Broughton, U Dhagat, TR Hercus, TL Nero, MA Grimbaldeston, ...
Immunological reviews 250 (1), 277-302, 2012
Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA
DB Ascher, J Wielens, TL Nero, L Doughty, CJ Morton, MW Parker
Scientific reports 4 (1), 1-12, 2014
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites
D Braig, TL Nero, HG Koch, B Kaiser, X Wang, JR Thiele, CJ Morton, ...
Nature communications 8 (1), 1-19, 2017
Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators
U Flierl, TL Nero, B Lim, JF Arthur, Y Yao, SM Jung, E Gitz, AY Pollitt, ...
Journal of Experimental Medicine 212 (2), 129-137, 2015
Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs)
CJ Burns, DG Bourke, L Andrau, X Bu, SA Charman, AC Donohue, ...
Bioorganic & medicinal chemistry letters 19 (20), 5887-5892, 2009
Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription
D Thomas, JA Powell, F Vergez, DH Segal, NYN Nguyen, A Baker, ...
Blood, The Journal of the American Society of Hematology 122 (5), 738-748, 2013
Signalling by the βc family of cytokines
TR Hercus, U Dhagat, WLT Kan, SE Broughton, TL Nero, M Perugini, ...
Cytokine & growth factor reviews 24 (3), 189-201, 2013
The βc receptor family–Structural insights and their functional implications
SE Broughton, TL Nero, U Dhagat, WL Kan, TR Hercus, D Tvorogov, ...
Cytokine 74 (2), 247-258, 2015
Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8α and C9
SE Wickham, EM Hotze, AJ Farrand, G Polekhina, TL Nero, S Tomlinson, ...
Journal of Biological Chemistry 286 (23), 20952-20962, 2011
Characterization of pathogenic human monoclonal autoantibodies against GM-CSF
Y Wang, CA Thomson, LL Allan, LM Jackson, M Olson, TR Hercus, ...
Proceedings of the National Academy of Sciences 110 (19), 7832-7837, 2013
Role of β-adrenergic receptor subtypes in lipolysis
SNS Louis, GP Jackman, TL Nero, D Iakovidis, WJ Louis
Cardiovascular drugs and therapy 14 (6), 565-577, 2000
Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody
SE Broughton, TR Hercus, MP Hardy, BJ McClure, TL Nero, M Dottore, ...
Cell reports 8 (2), 410-419, 2014
Synthesis, NMR studies and conformational analysis of oxazolidine derivatives of the β-adrenoreceptor antagonists metoprolol, atenolol and timolol
GP Moloney, DJ Craik, MN Iskander, TL Nero
Journal of the Chemical Society, Perkin Transactions 2, 199-206, 1998
Discovery and SAR of novel pyrazolo [1, 5-a] pyrimidines as inhibitors of CDK9
LJ Phillipson, DH Segal, TL Nero, MW Parker, S San Wan, M de Silva, ...
Bioorganic & medicinal chemistry 23 (19), 6280-6296, 2015
LK 204–545, a highly selective β1-adrenoceptor antagonist at human β-adrenoceptors
SNS Louis, TL Nero, D Iakovidis, GP Jackman, WJ Louis
European journal of pharmacology 367 (2-3), 431-435, 1999
The ‘Q‐band’absorption spectra of hematoporphyrin monomer and aggregate in aqueous solution
Photochemistry and photobiology 49 (1), 49-52, 1989
Conformational changes in the GM-CSF receptor suggest a molecular mechanism for affinity conversion and receptor signaling
SE Broughton, TR Hercus, TL Nero, M Dottore, BJ McClure, U Dhagat, ...
Structure 24 (8), 1271-1281, 2016
Protein structure and computational drug discovery
TL Nero, MW Parker, CJ Morton
Biochemical Society Transactions 46 (5), 1367-1379, 2018
Synthesis and β-adrenoceptor agonist properties of (▒)-1-(3', 4'-dihydroxyphenoxy)-3-(3", 4"-dimethoxyphenyl) ethylamino-2-propanol hydrochloride,(▒)-RO363. HCl, and the (2Sá…
D Iakovidis, SNS Louis, LA Rezmann, F Colagrande, TL Nero, ...
European journal of medicinal chemistry 34 (6), 539-548, 1999
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