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Edward Lesnefsky
Edward Lesnefsky
Professor of Internal Medicine, Virginia Commonwealth University
Verified email at vcuhealth.org
Title
Cited by
Cited by
Year
Production of reactive oxygen species by mitochondria: central role of complex III
Q Chen, EJ Vazquez, S Moghaddas, CL Hoppel, EJ Lesnefsky
Journal of Biological Chemistry 278 (38), 36027-36031, 2003
20062003
Function of mitochondrial Stat3 in cellular respiration
J Wegrzyn, R Potla, YJ Chwae, NBV Sepuri, Q Zhang, T Koeck, ...
Science 323 (5915), 793-797, 2009
11072009
Mitochondrial dysfunction in cardiac disease: ischemia–reperfusion, aging, and heart failure
EJ Lesnefsky, S Moghaddas, B Tandler, J Kerner, CL Hoppel
Journal of molecular and cellular cardiology 33 (6), 1065-1089, 2001
8992001
Intracoronary ultrasound imaging: correlation of plaque morphology with angiography, clinical syndrome and procedural results in patients undergoing coronary angioplasty
JMB Hodgson, KG Reddy, R Suneja, RN Nair, EJ Lesnefsky, ...
Journal of the American College of Cardiology 21 (1), 35-44, 1993
5271993
Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration
GM Strub, M Paillard, J Liang, L Gomez, JC Allegood, NC Hait, ...
The FASEB Journal 25 (2), 600, 2011
3972011
Ischemic defects in the electron transport chain increase the production of reactive oxygen species from isolated rat heart mitochondria
Q Chen, S Moghaddas, CL Hoppel, EJ Lesnefsky
American Journal of Physiology-Cell Physiology 294 (2), C460-C466, 2008
3622008
Mitochondrial dysfunction and myocardial ischemia-reperfusion: implications for novel therapies
EJ Lesnefsky, Q Chen, B Tandler, CL Hoppel
Annual review of pharmacology and toxicology 57, 535-565, 2017
3612017
Modulation of electron transport protects cardiac mitochondria and decreases myocardial injury during ischemia and reperfusion
Q Chen, AKS Camara, DF Stowe, CL Hoppel, EJ Lesnefsky
American Journal of Physiology-Cell Physiology 292 (1), C137-C147, 2007
3332007
Myocardial ischemia decreases oxidative phosphorylation through cytochrome oxidase in subsarcolemmal mitochondria
EJ Lesnefsky, B Tandler, J Ye, TJ Slabe, J Turkaly, CL Hoppel
American Journal of Physiology-Heart and Circulatory Physiology 273 (3 …, 1997
3071997
Mitochondrial metabolism in aging heart
EJ Lesnefsky, Q Chen, CL Hoppel
Circulation research 118 (10), 1593-1611, 2016
2972016
Aging selectively decreases oxidative capacity in rat heart interfibrillar mitochondria
SW Fannin, EJ Lesnefsky, TJ Slabe, MO Hassan, CL Hoppel
Archives of biochemistry and biophysics 372 (2), 399-407, 1999
2911999
Blockade of electron transport during ischemia protects cardiac mitochondria
EJ Lesnefsky, Q Chen, S Moghaddas, MO Hassan, B Tandler, CL Hoppel
Journal of Biological Chemistry 279 (46), 47961-47967, 2004
2682004
Reversible blockade of electron transport during ischemia protects mitochondria and decreases myocardial injury following reperfusion
Q Chen, S Moghaddas, CL Hoppel, EJ Lesnefsky
Journal of Pharmacology and Experimental Therapeutics 319 (3), 1405-1412, 2006
2522006
Mitochondrial-targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation …
K Szczepanek, Q Chen, M Derecka, FN Salloum, Q Zhang, M Szelag, ...
Journal of Biological Chemistry 286 (34), 29610-29620, 2011
2412011
Myocardial ischemia selectively depletes cardiolipin in rabbit heart subsarcolemmal mitochondria
EJ Lesnefsky, TJ Slabe, MSK Stoll, PE Minkler, CL Hoppel
American Journal of Physiology-Heart and Circulatory Physiology 280 (6 …, 2001
2392001
Oxidative phosphorylation and aging
EJ Lesnefsky, CL Hoppel
Ageing research reviews 5 (4), 402-433, 2006
2162006
Potential therapeutic benefits of strategies directed to mitochondria
AKS Camara, EJ Lesnefsky, DF Stowe
Antioxidants & redox signaling 13 (3), 279-347, 2010
2122010
Ischemic injury to mitochondrial electron transport in the aging heart: damage to the iron–sulfur protein subunit of electron transport complex III
EJ Lesnefsky, TI Gudz, CT Migita, M Ikeda-Saito, MO Hassan, PJ Turkaly, ...
Archives of biochemistry and biophysics 385 (1), 117-128, 2001
2022001
Mitochondrial localized Stat3 promotes breast cancer growth via phosphorylation of serine 727
Q Zhang, V Raje, VA Yakovlev, A Yacoub, K Szczepanek, J Meier, ...
Journal of Biological Chemistry 288 (43), 31280-31288, 2013
1932013
Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension
J Gomez-Arroyo, S Mizuno, K Szczepanek, B Van Tassell, R Natarajan, ...
Circulation: Heart Failure 6 (1), 136-144, 2013
1922013
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